Nonspecific Interstitial Pneumonia (NSIP), Confirmed by Open Lung Biopsy

Radiologic Findings

Serial chest radiographs: Multifocal patchy opacities in both lungs, particularly in peripheral and lower lungs. Gradual progression of disease for 5 months
Chest HRCT scans: Patchy consolidation and ground-glass attenuation in both lungs, particularly in peripheral and lower lungs, progression of disease in FU HRCT scan.

Brief Discussion

Etiologic factors of NSIP:
   
connective tissue disease 16%
   organic dust 17%
   acute lung injury 8%
   undiagnosed UIP
   nonrepresntative biopsy of BOOP.

Prognosis of NSIP:
   alive and well 45%
   alive with disease 38%
   dead of disease 11%
   dead of other 8%

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