Malignant Fibrous Tumor of the Pleura

Brief Discussion

Confirmed by operation.

Criteria for a judgement of malignancy
- high cellularity
- high mitotic activity (more than four mitotic figures per 10 high-power fields)
- pleomorphism
- hemorrhage
- necrosis      (Am J Surg Pathol 1989; 13: 640-658)

Gross findings that distinguished benign from malignant tumors
- more than 10cm
- less pedunculated
- atypical sites (parietal pleura of the chest wall, diaphragm, or mediastinum)
- necrosis and hemorrhage

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