Brief Discussions
Synonyms : plasma cell granuloma, inflammatory myofibroblastic tumor, histiocytoma, xanthoma, fibroxanthoma..
Inflammatory
Pseudotumor
Pathologic
Findings
Spindle-shaped
fibroblasts, permeation of collagen with lymphocytes, fibrosis, granulomatous
inflammation, lymphoid hyperplasia, intraalveolar fibrosis
Brief
Discussions
Synonyms
: plasma cell granuloma, inflammatory myofibroblastic tumor, histiocytoma, xanthoma,
fibroxanthoma..
Uncommon cause of the SPN : 0.7% of lung tumor
Generally regarded as a reactive process
- May mimic neoplasia : vertebral destruction, vascular invasion, recurrence, metastatic spread
Relationship
between inflammatory pseudotumor and malignancy is controversial
Solitary,
peripheral, sharply circumscribed, lobulated mass with lower lobe predilection
CT : Well-marginated and lobulated mass, heterogeneous attenuation with variable patterns of contrast enhancement and calcification (15 cases among the 61 pts : 25%)
MRI : Intermediate SI on T1WI and high SI on T2WI with variable enhancement