대한흉부영상의학회 Korean Society of Thoracic Radiology

Discussion

Diagnosis With Brief Discussion

Diagnosis

Pulmonary placental transmogrification

Radiologic Findings

Fig. 1. Chest PA shows probable thin-walled cavity or cyst in right mid lung zone.
Fig 2.(A) Lung window Chest CT scan (1-mm slice thickness) shows about 2-cm size nodule limited by thin wall and contains air with eccentric mural nodule in right upper lobe. (B, C) Thin section (1 mm) CT scan obtained using mediastinal window settings shows that central part of nodule contains soft-tissue and fat-tissue (–30 H) attenuating components with mild contrast enhancement (about 10HU).

Brief Review

Pulmonary placental transmogrification is a benign lesion, first described in 1979, unusual locally destructive lesion in lung, related to emphysematous bulla. It occurs in men between 20 to 50 years old.Histologically, pulmonary placental transmogrification resembles immature placental structures (villus-like papillary), but the tissues do not bear any biologic properties of the placenta. Placental transmogrification is not only associated with cystic or emphysematous lung lesion, but also with pulmonary fibrochondromatous hamartomas and pulmonary lipomatosis. Thus, the radiologic presentation can be bullous change or pulmonary lung nodules. the prognosis after surgical resection is excellent.

References

1. JW Kim, IH Park, W Kwon, MS Eom, YJ Kim, JH Oh.Placental Transmogrification of the Lung. KJR 2013 Nov-Dec; 14(6): 977–980.
2. G. R. Ferretti1, M. Kocier1, D. Moro-Sibilot2, P. Y. Brichon. Placental Transmogrification of the Lung: CT–Pathologic Correlation of a Rare Pulmonary Nodule. American Journal of Roentgenology. 2004;183: 99-101.
3. Fidler ME, Koomen M, Sebek B, Greco MA, Rizk CC, Askin FB. Placental transmogrification of the lung: a histologic variant of giant bullous emphysema—clinicopathological study of three further cases. Am J SurgPathol 1995; 19:563 –570

Keywords

Lung, Others,