Weekly Chest CasesArchive of Old Cases

Case No : 1083 Date 2018-07-29

  • Courtesy of Joosung Sun, Kyung Joo Park, MD. / Ajou University Medical Center
  • Age/Sex 61 / M
  • Chief ComplaintIncidental finding
  • Figure 1
  • Figure 2

Diagnosis With Brief Discussion

Diagnosis
Pulmonary placental transmogrification
Radiologic Findings
Fig. 1. Chest PA shows probable thin-walled cavity or cyst in right mid lung zone.
Fig 2.(A) Lung window Chest CT scan (1-mm slice thickness) shows about 2-cm size nodule limited by thin wall and contains air with eccentric mural nodule in right upper lobe. (B, C) Thin section (1 mm) CT scan obtained using mediastinal window settings shows that central part of nodule contains soft-tissue and fat-tissue (–30 H) attenuating components with mild contrast enhancement (about 10HU).
Brief Review
Pulmonary placental transmogrification is a benign lesion, first described in 1979, unusual locally destructive lesion in lung, related to emphysematous bulla. It occurs in men between 20 to 50 years old.Histologically, pulmonary placental transmogrification resembles immature placental structures (villus-like papillary), but the tissues do not bear any biologic properties of the placenta. Placental transmogrification is not only associated with cystic or emphysematous lung lesion, but also with pulmonary fibrochondromatous hamartomas and pulmonary lipomatosis. Thus, the radiologic presentation can be bullous change or pulmonary lung nodules. the prognosis after surgical resection is excellent.
References
1. JW Kim, IH Park, W Kwon, MS Eom, YJ Kim, JH Oh.Placental Transmogrification of the Lung. KJR 2013 Nov-Dec; 14(6): 977–980.
2. G. R. Ferretti1, M. Kocier1, D. Moro-Sibilot2, P. Y. Brichon. Placental Transmogrification of the Lung: CT–Pathologic Correlation of a Rare Pulmonary Nodule. American Journal of Roentgenology. 2004;183: 99-101.
3. Fidler ME, Koomen M, Sebek B, Greco MA, Rizk CC, Askin FB. Placental transmogrification of the lung: a histologic variant of giant bullous emphysema—clinicopathological study of three further cases. Am J SurgPathol 1995; 19:563 –570
Keywords
Lung, Others,

No. of Applicants : 83

▶ Correct Answer : 4/83,  4.8%
  • - Asan Medical Center , Korea (South) JOOAE CHOE
  • - Multimagem Diagn泥˜sticos , Brazil PEDRO PAULO TEIXEIRA E SILVA TORRES
  • - Chonnam National University Hwasun Hospital , Korea (South) JONG EUN LEE
  • - the first affiliatited hospital of nanjing medical univercity , China HAI XU
▶ Correct Answer as Differential Diagnosis : 1/83,  1.2%
  • - King Abdulaziz University Hospital , Saudi Arabia Amr M. Ajlan
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