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대한흉부영상의학회 Weekly Case 검색
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Weekly Chest CasesArchive of Old Cases

Case No : 330 Date 2004-02-21

  • Courtesy of Eun Jin Chae, M.D., Joon Beom Seo, M.D., Jae-Woo Song, M.D. / Asan Medical Center, Ulsan University, Seoul, Korea
  • Age/Sex 65 / M
  • Chief ComplaintDyspnea and febrile sense for 10 days
  • Figure 1
  • Figure 2
  • Figure 3
  • Figure 4
  • Figure 5

Diagnosis With Brief Discussion

Diagnosis
Amiodarone-induced pulmonary toxicity
Radiologic Findings
Previous chest radiograph shows patchy consolidation with reticular opacity in left lower lung field. Follow-up chest radiograph shows diffuse ground-glass opacity and consolidation with reticulation in both lungs. The patient has been treated with amiodarone because of atrial fibrillation. HRCT scans show multifocal areas of consolidation, ground-glass attenuation, and irregular linear opacities in both lungs. Mild traction bronchiectasis is noted within the consolidation. Open lung biopsy obtained from left upper lobe showed diffuse temporally uniform interstitial fibroblastic proliferation with multifocal hyaline membrane-like material in alveolar spaces, tightly clustered aggregates of intraalveolar macrophages and a few intraalveolar fibroblastic foci.
The histologic findings were consistent with amiodarone-induced acute interstitial pneumonia and BOOP feature.
Brief Review
Please refer to case 114 and 176
References
Please refer to case 114 and 176
Keywords
Lung, Iatrogenic lung disease, Drug complication,

No. of Applicants : 33

▶ Correct Answer : 22/33,  66.7%
  • - Annecy Hospital, France Gilles Genin
  • - Armed Forces Capital Hospital, Korea Chang Hyun Lee
  • - Centre d'imagerie Jacques Callot, Nancy, France Lionel Cannard
  • - CH Lyon sud, France Xavier Riviere
  • - CHU Nancy-Brabois, France Denis Regent
  • - Chungju Hospital, Konkuk University, Korea Chang Hee Lee
  • - CIM Saint Dizier, France JC Leclerc
  • - Dong-A University Hospital, Korea Ki-Nam Lee
  • - Geneva University Hospital, Switzerland Philippe Dumont
  • - Gwangmyoung Sung-Ae Hospital, Korea Jiyong Rhee
  • - Hangang SacredHeart Hospital, Korea Eil Seong Lee
  • - Homs National Hospital, Homs, Syria Rami Abou Zalaf
  • - Hospital Donostia, Spain Aitor Tilla
  • - Kangbuk Samsung Hospital, Korea Hyon Joo Kwag
  • - Maimonides Medical Center, N.Y., USA Naomi Twersky
  • - Mallinckrodt Institute of Radiology, USA Jin Mo Goo
  • - Nowon Eulji hospital, Korea Jeong Joo Woo
  • - Ondokuz Mayis University, Samsun, Turkey Cetin Celenk
  • - Samsung Medical Center, Korea Sung Shine Shim
  • - Social Security Hospital, Ankara, Turkey Meric Tuzun
  • - Sunlin Hospital, Korea Won Hyuk Shin
  • - Tokyo Kouseinenkin Hospital , Japan Noriatsu Ichiba
▶ Semi-Correct Answer : 3/33,  9.1%
  • - Clinic 1, Moscow, Russia Lepikhina Dasha
  • - Incheon Sarang Hospital, Korea Jung Hee Kim
  • - Escola Paulista de Medicina, Fleury, Sao Paulo - Brazil Gustavo Meirelles
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Each Case of This Site Supplied by the Members of KSTR.
Copyright of the Images is in the KSTR and Original Supplier.
Current Editor : Sung Shine Shim, MD, PhD. Email : sinisim@ewha.ac.kr

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