Discussion
Diagnosis With Brief Discussion
- Diagnosis
- Benign Metastasizing Leiomyoma
- Radiologic Findings
- On initial chest radiograph, multiple small nodular opacities were noted in both lung fields.Initial chest CT showed multiple small nodules in the bilateral lungs, and there was no evidence of calcification within the nodules.
Follow-up chest CT taken 13months later showed slightly increase in size of some of these nodules in the bilateral lungs. There was no evidence of mediastinal lymph node enlargement.
One month after the follow-up CT, the FDG PET was performed and showed no definite FDG uptakes of these nodules.
PHx> s/p TAH due to submucosal leiomyoma 11 months ago
Lung, percutaneous needle biopsy results: Consistent with leiomyoma (CD34: Negative, Desmin: Positive, Smooth muscle actin: Positive, S-100: Negative)
- Brief Review
- Pulmonary benign metastasizing leiomyoma from uterus is very rare and pathogenesis of this disease has not yet been elucidated. Most patients are pre-menopausal.
Sx: Asymptomatic (m/c)
Diagnosis: 1) history of uterine leiomyoma
2) Positive for SMA, Negative for S-100
3) Need for clinical correlation.
Radiologic feature;
multiple nodules in 87% of cases (70% bilateral nodules and 17% unilateral nodules)or as a solitary nodule in 13% of cases
- Please refer to
Case 394, Case 413, Case 667, -
- References
- 1. Koh DM, Burn PR, King DM. Benign metastasizing leiomyoma with intracaval leiomyomatosis, Br J Radiol. 2000;73;435-437
2. Fu Y, Li H, Tian B. Pulmonary benign metastasizing leiomyoma: a case report and review of the literature. World J Surg Oncol. 2012; 10:268
- Keywords
- Lung, Benign tumor,