Weekly Chest CasesImaging Conference Cases

Case No : 2

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  • Age/Sex 44 / F
  • Case Title Chest pain
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Diagnosis With Brief Discussion

Courtesy
Catholic University Youido St. Mary's Hospital, Seoul, Korea
Imaging Findings
Spindle-shaped fibroblasts, permeation of collagen with lymphocytes, fibrosis, granulomatous inflammation, lymphoid hyperplasia, intraalveolar fibrosis
Discussion
Synonyms : plasma cell granuloma, inflammatory myofibroblastic tumor, histiocytoma, xanthoma, fibroxanthoma..

Uncommon cause of the SPN : 0.7% of lung tumor

Generally regarded as a reactive process

- May mimic neoplasia : vertebral destruction, vascular invasion, recurrence, metastatic spread

Relationship between inflammatory pseudotumor and malignancy is controversial

Solitary, peripheral, sharply circumscribed, lobulated mass with lower lobe predilection

CT : Well-marginated and lobulated mass, heterogeneous attenuation with variable patterns of contrast enhancement and calcification (15 cases among the 61 pts : 25%)

MRI : Intermediate SI on T1WI and high SI on T2WI with variable enhancement
Reference
Synonyms : plasma cell granuloma, inflammatory myofibroblastic tumor, histiocytoma, xanthoma, fibroxanthoma..

Uncommon cause of the SPN : 0.7% of lung tumor

Generally regarded as a reactive process

- May mimic neoplasia : vertebral destruction, vascular invasion, recurrence, metastatic spread

Relationship between inflammatory pseudotumor and malignancy is controversial

Solitary, peripheral, sharply circumscribed, lobulated mass with lower lobe predilection

CT : Well-marginated and lobulated mass, heterogeneous attenuation with variable patterns of contrast enhancement and calcification (15 cases among the 61 pts : 25%)

MRI : Intermediate SI on T1WI and high SI on T2WI with variable enhancement
Keywords
Lung, Non-infectious inflammation,
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