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Weekly Chest CasesImaging Conference Cases

Case No : 5

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  • Age/Sex 69 / M
  • Case Title Hepatic mass on abdominal US
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Diagnosis With Brief Discussion

Discussion
The occurrence of noncaseating granuloma in patients with malignancy who have no symptoms or signs of systemic sarcoidosis

Nadel and Ackerman (1950) : 5 patients

: epidermoid carcinoma of the oral cavity(n=1), melanocarcinoma (n=1), breast carcinoma (n=1), cylindroma of the bronchus (n= 1), pancreas carcinoma (n=1)



Pathogenesis of sarcoidlike lesions

: not clear

: histologic reaction to an antigenic stimulus from the malignant tumor


Presence of sarcoidlike lesions have prognostic importance in patients with malignancy.



O`Conell MJ et al (1975)

: 91 patients treated for Hodgkin`s disease

: 17 had sarcoidlike reaction have fewer relapse, longer survival rate compared without granulomas.



Radiology 1996; 200:255-261

Keywords
Lung, Non-infectious inflammation, Sarcoidosis,
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