Discussion
Diagnosis With Brief Discussion
- Diagnosis
- Chronic eosinophilic pneumonia
- Radiologic Findings
- Chronic eosinophilic pneumonia is one of eosinophilic lung diseases of unknown cause. It is idiopathic condition characterized by chronic and progressive clinical features.
Clinical manifestation is usually insidious and the patient experiences symptoms for an average of 7.7 months before the diagnosis is made. Most patients are middle aged, and approximately 50% have asthma. Women are more frequently affected than men. Pulmonary function tests can be normal in mild cases but usually show restrictive defects. Peripheral blood eosinophilia is usually mild or moderate but occasionally is severe. Increased serum IgE levels are seen in two-thirds of patients. The erythrocyte sedimentation rate is usually elevated and peripheral blood thrombocytosis has also been reported. The percentage of eosinophils in the BAL fluid is very high.
The typical chest radiographic finding in CEP is nonsegmental peripheral airspace consolidation (“photographic negative shadow of pulmonaryedema”) involving mainly the upper lobes. However, this finding may be seen in less than 50% of cases.
CT demonstrates typical nonsegmental areas of airspace consolidation with peripheral predominance. Less common findings include ground-glass opacities, nodules, and reticulation. These less common findings predominate in the later stages of CEP. CT performed more than 2 months after the onset of symptoms shows linear bandlike opacities parallel to the pleural surface. Pleural effusion is observed in less than 10% of cases.
- Brief Review
- References
- Keywords
- Lung, Eosinophilic lung disease,