Discussion
Diagnosis With Brief Discussion
- Diagnosis
- Acute eosinophilic pneumonia (AEP)
- Radiologic Findings
- Fig 1. Chest radiograph shows diffuse irregular patchy opacities and increased interstitial markings in both lungs.
Fig 2-6. CT scan reveals multifocal ill-defined ground-glass opacities (GGO) with interlobular septal thickening in both lungs.
Bronchoalveolar lavage (BAL) showed 57% eosinophilia
- Brief Review
- 1. Cause - majority of cases are idiopathic
- Tobacco smoke be a trigger for AEP, especially in new-onset smokers
2. CT findings - Bilateral patchy GGO and consolidation
- Poorly ill-defined nodules
- Interlobular septal thickening
3. Diagnosed when the following combination clinical and radiographic findings
1) Acute febrile illness of less than 5 days’ duration
2) Hypoxemia
3) Diffuse alveolar or mixed alveolar-interstitial opacities
4) BAL fluid consisting of more than 25% eosinophils
5) Peripheral blood eosinophil percentages - usually normal
6) Absence of parasitic, fungal, or other infection
7) Prompt and complete response to corticosteroids
8) No relapse after discontinuation of corticosteroids
- References
- 1. Yeon Joo Jeong, et al. Eosinophilic lung diseases : A Clinical, Radiologic and Pathologic Overview. Radiographics 2007; 27: 617-639.
- Keywords