Discussion
Diagnosis With Brief Discussion
- Diagnosis
- Endobronchial actinomycosis and associated with broncholith and aspergillosis
- Radiologic Findings
- Fig 1. Chest PA shows ill-defined consolidation in the lateral aspect of right lower lung zone.
Fig 2-6. Chest CT with mediastinal window setting and lung setting shows ill-defined low-attenuation consolidation with inner calcification or broncholith in the anterior basal segment of RLL. Segmental bronchus is obstructed, resulting in tubular mucus bronchogram and obstructive pneumonia in the distal portion.
On bronchoscopic exam, there was a necrotic and brownish material obstructing the orifice of the anterior basal segmental bronchus of the right lower lobe. Bronchoscopic biopsy was done, and the histopathological examination revealed aggregated fungal hyphae and bacterial colonies, confirming the diagnosis of aspergillosis and actinomyces.
- Brief Review
- Endobronchial actinomycosis is a rare type of infection caused by the actinomyces. It results from colonization of preexisting obstructive broncholiths or endobronchial foreign bodies, which inflames the adjacent airway and causes distal obstructive pneumonia. Broncholiths are usually formed by erosion of calcified lymph nodes into the airway as a result of a granulomatous process. We speculate that a preexisting broncholith was secondarily infected by Actinomyces and Aspergillus, as one of the common co-pathogens for thoracic actinomycosis have been described as Aspergillus
On CT, endobronchial actinomycosis is seen as a proximal obstructive calcified endobronchial nodule with distal obstructive pneumonia of the involved lobe or segment. Distal post-obstructive pneumonic consolidation usually shows a central low-attenuation area with or without cavities.
- References
- Keywords