Discussion
Diagnosis With Brief Discussion
- Diagnosis
- Endobronchial Actinomycosis
- Radiologic Findings
- Figure 1. Chest PA shows nodular infiltrations in the left lower lobe.
Figures 2-4. Contrast-enhanced CT scans with mediastinal window setting revealed a calcified nodular dense lesion within the left lower lobe posterobasal segemtal bronchus.
Distal bronchi were filled with mucus plugs.
Figure 5. Chest CT scan with lung window setting shows multiple centrilobular nodules associated with bronchial obstruction.
Bronchoscopy showed a yellowish white hard mass occluding the bronchial lumen at the LLL posteroobasal segmental bronchus. The mass was removed with bronchoscopic forceps.
Histological examination of biopsied material was compatible with actinomycosis.
- Brief Review
- Primary endobronchial actinomycosis is rare, and only several cases have been reported in the literature. In some reports, endobronchial actinomycosis has been associated with foreign body aspiration. The formation of broncholiths may result from de novo calcification secondary to chronic inflammation associated with actinomycotic infection, and may be associated with aspirated materials.
The most common granulomatous infections associated with broncholithiasis include H. capsulatum and M. tuberculosis. The mediastinal lymph node involved in the granulomatous process becomes calcified into indivicual masses, and ultimately erode in the airway. The other differential diagnosis for the endobronchial calcified mass includes foreign bodies and calcified endobronchial neoplasm. Although it is very rare, endobronchial actinomycosis should be included in the differential dignosis of calcified endobronchial masses, especially when there is no clinical or radiological evidence of a granulomatous infection, such as tuberculosis, and the yellowish materials obstructing the bronchus are seen during bronchoscopy.
- References
- 1. Seo JB, Lee JW, Ha SY, Park JW, Jeong SH, Park GY. Primary endobronchial actinomycosis associated with broncholithiasis. Respiration 2003;70:110-113
- Keywords
- Airway, Lung, Infection, Bacterial infection,