Discussion
Diagnosis With Brief Discussion
- Diagnosis
- Chondrosarcoma
- Radiologic Findings
- Posteroanterior and left lateral chest radiographs show right anterior chest wall mass.
Contrast enhanced axial CT images show a low attenuation mass replacing right 2nd rib and costal cartilage.
The mass contains chondroid mineralization.
CT scans also demonstrate multiple mediastinal lymphadenopathy and pleural metastasis.
- Brief Review
- The vast majority of solitary lesions (not associated with enchondromatosis) with chondroid matrix mineralization in the ribs and sternum are chondrosarcomas, and solitary enchondromas are extremely rare. Occasionally, chondrosarcomas in the ribs and sternum may be discovered incidentally at chest radiography. Patients are often somewhat younger than those with conventional chondrosarcomas in other sites. Rib lesions usually involve the anterior rib at the costochondral junction and show osseous expansile remodeling with a ring-and-arc pattern of calcification and soft-tissue extension on both radiographs and CT.
The soft tissue component frequently reveals typical punctuate or ring-and-arc matrix mineralization and a lobular growth pattern. The nonmineralized components, both intraosseous and extraosseous, typically have low attenuation on CT scans, reflecting the high water content of hyaline cartilage. CT performed after intravenous administration of contrast material demonstrates mild peripheral rim and septal enhancement. Higher-grade lesions may show higher CT attenuation, similar to that of muscle, and more prominent diffuse or nodular contrast enhancement, caused by increased cellularity and resultant reduced water content.
- References
- RadioGraphics 2003; 23:1245?278
- Keywords
- Chest wall, Malignant tumor,