Discussion
Diagnosis With Brief Discussion
- Diagnosis
- Lymphangiogleiomyomatosis
- Radiologic Findings
- Posteroanterior chest radiograph shows subtle reticular densities in both lungs. CT scans show innumerable, thin-walled cysts in both lung fields without zonal predominance.

- Brief Review
- .Women of reproductive age
.Symptom
- recurrent spontaenous pneumothorax, slowly progressive dyspnea, hemoptysis, chylothorax, chylous ascites
.Pathologic findings
- proliferation of immature appearing smooth muscle cells (LAM cells) in the lungs and axial lymphatics in the thorax and abdomen
- formation of thin-walled pulmonary cysts
.Extrathoracic involvement
- kidney(angiomyolipoma), retroperitoneal LN enlargement, related with tuberous sclerosis (TSC-LAM)
.Radiographic findings
- generalized, symmetric, reticular or reticulonodular opacities
- preserved or increased lung volumes, pneumothorax, pleural effusion (secondary to chylothorax)
.CT findings
- Numerous thin-walled cysts surrounded by normal lung parenchyma with diffuse, random and bilateral distribution
- Cysts typically ranges from 2-5mm in diameter but have been reported to be as large as 25mm
- Round, polygonal and ovoid in shape
- Cyst wall thickness ranges from barely perceptable to 2mm thick in most cases
- References
- Keywords
- Lung, Interstitial lung disease, LAM, ILD,