Discussion
Diagnosis With Brief Discussion
- Diagnosis
- Pulmonary mucormycosis
- Radiologic Findings
- Mucormyocosis is an infectious disease by fungi in the class Zygomycetes, most commonly in the order Mucorales. Mucormycosis occurs almost invariably in patients who are not fully inmmunocompetent. Patients with diabetes, a renal transplant, or a hematologic malignancy are particularly susceptible. Mucormycosis may present as an infection of the upper respiratory tract (particularly the sinuses) or the lungs. Individuals with pulmonary mucormycosis tend to be more severely immunosuppressed, for example recipients of bone marrow transplantation.
The most common radiographic abnormality is lobar consolidation. The consolidation may be multilobar but can be focal and mass-like lesion. Occasionally there may be pleural effusions or hilar lymphadenopathy. Because of the angioinvasive nature of mucormycosis, the mass-like lesions may accompany the peripheral halo on CT (CT-halo sign), representing the perilesional hemorrhage, pathologically. Once infarction has occurred, cavitation within the necrotic lung ensues.
Treatment for mucormycosis depends on antifungal agents, surgery, and control of predisposing conditions.
- Brief Review
- References
- 1. Jonathan H. Chung , MD, et al. Pulmonary Mucormycosis . Radiology 2010; 256:667
- Keywords
- lung, infection, fungal,