Discussion
Diagnosis With Brief Discussion
- Diagnosis
- Lipoid pneumonia
- Radiologic Findings
- Fig. 1-2. Chest PA and lateral images show diffuse ill-defined nodules and consolidations in both lower lung zones, which accompanied with air-bronchogram and both cardiac margins obliteration.
Fig. 3-7 Chest CT axial images (lung window setting) show multifocal ill-defined centrilobular nodules and diffuse ill-defined ground glass opacities in both lungs (both lower lobe predominant). Also, it is revealed minimal traction bronchiectasis and crazy-paving appearance within ill-defined ground glass opacities.
- Brief Review
- Since DOE symptom did not improve despite appropriate treatment, the TBLB was performed for patient histological examination. Histologic findings (H&E stain) represent mature adipose tissue present in bronchiole and lung parenchyme (red circle and blue arrows). This was a finding consistent with lipoid pneumonia. After the patient was diagnosed on lipoid pneumonia, when the patient's medical drug history was taken again, it was found that the patient had been taking squalene in a liquid pouch (not capsule form) by tearing open the plastic pouch and ingesting it during about 3 months. This type of squalene is thought to be much more likely (be larger amount of aspiration) to result in aspiration of the contents in elderly patients compared to the capsule type.
- References
- Keywords