대한흉부영상의학회 Korean Society of Thoracic Radiology

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Weekly Chest CasesArchive of Old Cases

Case No : 1450 Date 2025-08-04

  • Courtesy of Woo Hyeon Lim / Seoul National University Hospital
  • Age/Sex 29 / F
  • Chief ComplaintRadiologic abnormality, Sjogren syndrome
  • Figure 1
  • Figure 2
  • Figure 3

Diagnosis With Brief Discussion

Diagnosis
Thymic MALT lymphoma
Radiologic Findings
Mucosa-associated lymphoid tissue (MALT) lymphoma is a low-grade B cell lymphoma, and thmic MALT lymphoma is rare. Thymic MALT lymphoma has been documented primarily in Asian women, and about 80% of thymic MALT lymphoma cases are associated with autoimmune disorders, most of which are Sjogren syndrome. On images, thymic MALT lymphomas usually appear as solid and cystic anterior mediastinal masses. The prognosis for thymic MALT lymphoma is considered to be good, and one meta-analysis reported that 5-year overall survival was 97.2%.
Brief Review
1. Zhou MX, Chen YY, Zhang JQ, et al. A systematic review and meta-analysis of thymic mucosa-associated lymphoid tissue lymphoma. J Thorac Dis. 2022;14:2894-2907.
2. Fu MY, O’Neill R, Silverstone EJ, et al. Primary thymic mucosa-associated lymphoid tissue (MALT) lymphoma with Sjogren's syndrome and diffuse cystic lung disease: a complex respiratory presentation of a multifaceted autoimmune disease. BMJ Case Rep. 2024;17:e259587.
3. Shigenobu T, Suzuki T, Hayashi H, et al. Thymic MALT lymphoma associated with Sjögren’s syndrome with postoperative cardiac tamponade and acute pleuritis: a case report. World J Surg Oncol. 2024;22:160.
References
Keywords

No. of Applicants : 69

▶ Correct Answer : 34/69,  49.3%
  • - Funabashi General Hospital , Japan MANABU AKIMOTO
  • - medical scanning , Japan HIROAKI ARAKAWA
  • - IUHW Narita Hospital , Japan ISSEI FUKUDA
  • - ZIGONG TCM HOSPITAL OF CHINA , China CAO CUN YOU
  • - Affilitated Hospital of Jining Medical college , China JIANG SHENG HUA
  • - , Italy PAOLO BALDASSARI
  • - Teikyo University Hospital , Japan CHIAKI SATO
  • - , Korea (South) JIN YOUNG LEE
  • - , China FANG YING GEN
  • - Secomedic Hospital , Japan FUMINORI MIYOSHI
  • - Oita University, Faculty of Medicine , Japan FUMITO OKADA
  • - , Korea (South) KANGHWI LEE
  • - university of montreal , Canada Andrei Bogdan Gorgos I
  • - University of Yamanashi , Japan HIROYUKI MORISAKA
  • - University of Yamanashi , Japan HIROAKI WATANABE
  • - Narayana Multispeciality Hospital Jaipur Rajasthan , India JAINENDRA JAIN
  • - Yonsei University,Severance Hospital , Korea (South) JUN GU KANG
  • - , Japan SHUNJIRO NOGUCHI
  • - , Korea (South) HEONSEOK LEE
  • - Jichi Medical University, School of Medicine , Japan MITSURU MATSUKI
  • - University of Tsukuba, Dept of Radiology , Japan MANABU MINAMI
  • - Avrasya Hospital/ISTANBUL , Turkey MURAT ULUSOY
  • - Other , Korea (South) SEOL A LEE
  • - Kyoto University , Japan SHO KOYASU
  • - Kobe Children , Japan SHUHEI NORIMOTO
  • - Seoul National University Bundang Hospital , Korea (South) YOONAH DO
  • - CHA University, CHA Bundang Medical Center , Korea (South) HWANGSEON JU
  • - Yonsei University,Severance Hospital , Korea (South) SEO BUM CHO
  • - , Japan YUMI MAEHARA
  • - Toyota Kosei Hospital , Japan YUKI HAYASHI
  • - the first affiliatited hospital of nanjing medical univercity , China HAI XU
  • - University of Yamanashi , Japan KOJIRO ONOHARA
  • - , Japan JUN YOSHIDA
  • - Jiangsu province hospital , China WANGJIAN ZHA
▶ Correct Answer as Differential Diagnosis : 23/69,  33.3%
  • - Saitama-Sekishinkai Hosptal , Japan MIHOKO YAMAZAKI
  • - , Japan SUZUNE TSUKAMOTO
  • - Shiga University of Medical Science , Japan AKITOSHI INOUE
  • - Kyoto University , Japan AKIHIKO SAKATA
  • - McGill University Health Center , Canada ALEXANDRE SEMIONOV
  • - Oita university , Japan AYUMI KAMEI
  • - Kyoto City Hospital , Japan YUSUKE UTSUNOMIYA
  • - Healthy Longevity Medical Center , Japan SHIN-ICHI CHO
  • - University of Yamanashi , Japan TAKAAKI HASHIMOTO
  • - Osaka University , Japan AKINORI HATA
  • - The University of Tokyo Hospital , Japan TOSHIHIRO FURUTA
  • - , Japan YOSHIKI ISHII
  • - Chonbuk National University Hospital , Korea (South) YEEUN LEE
  • - Osaka Metropolitan University Hospital , Japan SHU MATSUSHITA
  • - Shiga General Hospital , Japan YUSAKU MORIBATA
  • - , Taiwan SHIH HAN PAN
  • - Osaka metropolitan university Hospital , Japan TATSUSHI OURA
  • - GHICL , France MANUEL TOLEDANO
  • - Korea University Anam Hospital , Korea (South) KYU-CHONG LEE
  • - , Japan MATSUNO MAI
  • - Fukuoka university , Japan KEISUKE SATO
  • - Kantou Rousai Hospital , Japan KAORU SUMIDA
  • - Chonbuk National University Hospital , Korea (South) HYEONG RYUN CHO
▶ Semi-Correct Answer : 1/69,  1.4%
  • - Kyung Hee University Medical Hospital , Korea (South) JEONG TAEK YOON
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