대한흉부영상의학회 Korean Society of Thoracic Radiology

Discussion

Diagnosis With Brief Discussion

Diagnosis

Atypical Carcinoid

Radiologic Findings

Atypical carcinoids have clinicopathologic features intermediate between the typical carcinoids and small cell carcinomas. Unlike typical carcinoids, the majority of atypical carcinoids are peripheral (50-100%), are associated with a history of cigarette smoking (83-94%), occur more often in men (2:1) and tend to occur in a slightly older age group (mean age in fifties to sixties).
The histopathologic features that distinguish atypical carcinoid from typical carcinoid are: (1) increased mitotic activity ( an average of 10 mitoses per 10 high power fields); (2) greater cytological pleomorphism with larger, vesicular nuclei, larger, more frequent nucleoli and higher nuclear to cytoplasmic ratios; (3) increased cellularity and architectural irregularities; and (4) tumor necrosis.
The radiographic features of atypical carcinoids of the lung are a round or ovoid shaped, 1.5 to 10 cm sized, contrast-enhancing, peripheral mass (21/32). These masses showed slight to marked lobulation(15/21), and although some are smoothly bordered, but others exhibited a spiculated margin. Less commonly, they included multilobulated masses, a thin-walled cavity, lobar atelectasis without demonstrable mass.

Brief Review

References

Keywords

Lung, Malignant tumor,