대한흉부영상의학회 Korean Society of Thoracic Radiology GuerBet

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대한흉부영상의학회 Weekly Case 검색
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Weekly Chest CasesArchive of Old Cases

Case No : 26 Date 1998-04-27

  • Courtesy of Yo Won Choi, M.D. / Hanyang Univercity Hospital
  • Age/Sex 76 / F
  • Chief Complaintfever and chill for several days
  • Figure 1
  • Figure 2
  • Figure 3

Diagnosis With Brief Discussion

Diagnosis
Endobronchial Hamartoma
Radiologic Findings
Hamartoma can be defined as a developmental malformation composed of tissues that normally constitute the organ in which the tumor occurs, but in which the tissue elements, although mature, are disorganized. In the lung, the term traditionally refers to a well-circumscribed tumor consisting predominantly of cartilarge and adipose tissue. In recent years, several authors have proposed that they are best regarded as benign neoplasms, probably derived from an undifferentiated bronchial wall mesenchymal cell.
Hamartomas are uncommon pulmonary neoplasms (5.7% of 2958 solitary lung lesions). Most are discovered in adulthood, with a peak incidence in the sixth decade. The tumors occur most often in males (2~3 times). Approximately 90% of pulmonary hamartomas are located within the parenchyma, usually in a peripheral location. Endobronchial hamartoma is a special form of the usual intrapulmonary hamartoma, which originates from a large bronchus, grows into the lumen, and obstructs the bronchi before it grows big. Most endobronchial tumors, therefore, produce symptoms, such as cough and fever, due to bronchial obstruction.
Endobronchial hamartomas most often appear as fleshy, polypoid tumors attached to the bronchial wall by a narrow stalk. The central portion is usually composed of a core of adipose tissue surrounded by somewhat compressed loose fibrous tissue. Smooth muscle, seromucinous glands, and myxomatous tissue may be admixed. Cartilage is often absent or present in small amounts. In a small percentage of cases, bronchial obstruction leads to atelectasis, obstructive pneumonitis, and progressive peripheral lung destruction. Whenever a fatty endobronchial mass is identified on CT scans, the differential diagnosis should be narrowed to lipoma and hamartoma.
Brief Review
References
Keywords
Airway, Benign tumor,

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