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Case No : 951 Date 2016-01-18
- Courtesy of So Won Lee, Yoo Na Kim, Myung Jin Chung / Samsung Medical Center
- Age/Sex 26 / F
- Chief ComplaintRight shoulder pain for two months
Discussion
Diagnosis With Brief Discussion
- Diagnosis
- Intrathymic parathyroid adenoma
- Radiologic Findings
- Contrast-enhanced chest CT demonstrates a well-enhancing mass with internal low-attenuated cystic change in the right anterior mediastinum. Elevated Serum PTH level (2811.2 pg/ml) and hypercalcemia suggested hyperparathyroidism. Tc-99 Sestamibi (MIBI) scan showed persistent abnormal uptake in the right anterior mediastinal mass. Mediastinal mass excision was performed, and the pathology confirmed an intra-thymic parathyroid adenoma.
An osteolytic lesion involving right scapula proved to be a giant cell lesion compatible with brown tumor, which is one of the manifestations of hyperparathyroidism.
- Brief Review
- Most common sites of ectopic location of parathyroid adenoma include thymus, tracheo-esophageal groove, carotid sheath, intrathyroid and para-esophageal locations. The hyper-functioning adenoma is ectopically placed in the mediastinum in 1
- References
- 1. Paige B. Clark, Nancy D. Perrier, Kathryn A. Morton. Detection of an Intrathymic Parathyroid Adenoma Using Single-Photon Emission CT 99mTc Sestamibi Scintigraphy and CT. AJR 2005;184:S16
- Keywords
- Mediastinum, Benign tumor,
No. of Applicants : 105
- ▶ Correct Answer : 6/105, 5.7%
-
- - Juntendo University Hospital , Japan Akifumi Hagiwara
- - �stanbul , Turkey Ayhan Yilmaz
- - Niigata City General Hospital , Japan Takao Kiguchi
- - Seirei Hamamatsu General Hospital , Japan Kenichi Mizuki
- - Asan , Korea (South) Sania ALBlushi
- - National Center hospital of Neurology and Psychiatry , Japan Kaoru Sumida
- ▶ Correct Answer as Differential Diagnosis : 9/105, 8.6%
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- - NIMS, HYDERABAD , India bhaskar kakarla
- - Saitama-Sekishinkai Hosptal , Japan Mihoko Yamazaki
- - King Abdulaziz University Hospital , Saudi Arabia Amr Ajlan
- - The University of Tokyo Hospital , Japan Toshihiro Furuta
- - Fortis hospital , Mohali , India Shaleen Rana
- - McGill University Health Center , Canada Alexandre Semionov
- - okayama university , Japan numa shingo
- - Kinki University Faculty of Medicine, , Japan Mitsuru Matsuki
- - Medicheck health care , Korea (South) Chae Lim
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