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Weekly Chest CasesArchive of Old Cases

Case No : 1364 Date 2023-12-12

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  • Courtesy of Sung Shine Shim, Woocheol Kwon / Ewha Womans University Seoul Hospital
  • Age/Sex 81 / F
  • Chief ComplaintBoth lower extremities (proximal limb) weakness for 3 months
  • Figure 1
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  • Figure 3
  • Figure 4
  • Figure 5
  • Figure 6
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Diagnosis With Brief Discussion

Diagnosis
small cell cancer associated with Lambert-Eaton myasthenic syndrome
Radiologic Findings
Histological examination of bronchoscopic-guided biopsy disclosed small cell lung cancer. Following a diagnosis of LEMS, the patient underwent one course of cisplatin + etoposide chemotherapy.

Fig 1-3. Chest CT images show an enhancing mass in subcarina and enlarged LNs in paratracheal area.
Fig 4-5. On the fused PET/CT images, the mass and LNs show focal hypermetabolic uptake.
Fig 6-7. Lung window setting of CT images show multifocal bronchiectasis with bronchiolitis. Decreased volume of left lung combined with effusion is noted.
Brief Review
The Lambert
References
1. ONeill JH, Murray NMF, Newsom-Davis J. The Lambert-Eaton myasthenic syndrome
Keywords

No. of Applicants : 70

▶ Correct Answer : 22/70,  31.4%
  • - Ishikawa Matto Central Hospital , Japan MANABU AKIMOTO
  • - Saitama-Sekishinkai Hosptal , Japan MIHOKO YAMAZAKI
  • - , Japan SUZUNE TSUKAMOTO
  • - , Japan HIROAKI ARAKAWA
  • - Healthy Longevity Medical Center , Japan SHIN-ICHI CHO
  • - Oita University, Faculty of Medicine , Japan FUMITO OKADA
  • - Qatif Central Hospital , Saudi Arabia HANI MAKKY ALSALAM
  • - Yokkaichi municipal hospital , Japan HIKARI FUKUI
  • - , Japan KENTARO KOTANI
  • - , Japan SHUNJIRO NOGUCHI
  • - Tokyo Medical and Dental University , Japan MIKIYA FUJII
  • - Osaka metropolitan university Hospital , Japan TATSUSHI OURA
  • - GHICL , France MANUEL TOLEDANO
  • - Hyogo Prefectural Kobe Children , Japan SHUHEI NORIMOTO
  • - Yonsei University,Severance Hospital , Korea (South) SEO BUM CHO
  • - Fukuoka university , Japan KEISUKE SATO
  • - Ichinomiya Nishi Hospital , Japan Takao Kiguchi
  • - Nerimahikarigaoka hospital , Japan TAKANA HAYASHI
  • - , Japan YUMI MAEHARA
  • - Toyota Kosei Hospital , Japan YUKI HAYASHI
  • - , China LI GUO
  • - Jiangsu province hospital , China WANGJIAN ZHA
▶ Correct Answer as Differential Diagnosis : 5/70,  7.1%
  • - , Japan KYOKO NAGAI
  • - McGill University Health Center , Canada ALEXANDRE SEMIONOV
  • - Vita Hospital , Brazil DIOGO LAGO PINHEIRO
  • - University of Tsukuba, Dept of Radiology , Japan MANABU MINAMI
  • - The Catholic University of Korea Yoeuido St. Mary , Korea (South) CHAWOONG JEON
▶ Semi-Correct Answer : 2/70,  2.9%
  • - Others , India PURUSHOTHAMA RAO TUMMALA
  • - Matsunami General Hospital , Japan TARO TAKEDA
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Current Editor : Eui Jin Hwang, M.D., Ph.D Email : weeklychestcases@gmail.com

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