Weekly Chest CasesArchive of Old Cases

Case No : 1387 Date 2024-05-21

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  • Courtesy of Hee Kang / Kosin University Gospel Hospital
  • Age/Sex 63 / M
  • Chief ComplaintMild dyspnea and fatigue
  • Figure 1
  • Figure 2
  • Figure 3
  • Figure 4
  • Figure 5

Diagnosis With Brief Discussion

Diagnosis
multiple myeloma with thoracic paraskeletal involvement
Radiologic Findings
He was diagnosed with multiple myeloma with thoracic paraskeletal involvement through VATS biopsy and bone marrow biopsy.

Figure 1. Chest radiography reveals bilateral pleural effusions, with more on the left side. Additionally, there were somewhat increased bronchovascular bundle markings and ill-defined patchy opacities in both hemithoraces.

Figure 2. Axial view contrast-enhanced chest CT scan reveals multifocal pleural nodular lesions and pleural effusion in both hemithoraces.

Figure 3. On the oblique axial reconstruction image, the lesions appear as a continuous band-like soft tissue density with a smooth margin along each rib.

Figure 4. 5 On the coronal and sagittal images, the lesions are surrounding the inner surface of each rib.
Brief Review
Multiple myeloma (MM) is the most frequent cancer to involve the skeleton, with 80
References
1. Blade J, Fernandez de Larrea C, Rosinol L, Cibeira MT, Jimenez R, Powles R. Soft-tissue plasmacytomas in multiple myeloma: incidence, mechanisms of extramedullary spread, and treatment approach. J Clin Oncol 2011;29:3805-12.
2. Blade J, Beksac M, Caers J, et al. Extramedullary disease in multiple myeloma: a systematic literature review. Blood Cancer J 2022;12:45.
Keywords

No. of Applicants : 76

▶ Correct Answer : 2/76,  2.6%
  • - Saitama-Sekishinkai Hosptal , Japan MIHOKO YAMAZAKI
  • - Toyota Kosei Hospital , Japan YUKI HAYASHI
▶ Correct Answer as Differential Diagnosis : 14/76,  18.4%
  • - Fukuoka university , Japan KEISUKE SATO
  • - University of Yamanashi , Japan TAKAAKI HASHIMOTO
  • - Ichinomiya Nishi Hospital , Japan Takao Kiguchi
  • - The Catholic University of Korea Yoeuido St. Mary , Korea (South) CHAWOONG JEON
  • - The University of Tokyo Hospital , Japan TOSHIHIRO FURUTA
  • - Shiga University of Medical Science , Japan AKITOSHI INOUE
  • - Other , Korea (South) SEOL A LEE
  • - , Korea (South) JIN WOO YOON
  • - Healthy Longevity Medical Center , Japan SHIN-ICHI CHO
  • - Vita Hospital , Brazil DIOGO LAGO PINHEIRO
  • - the first affiliatited hospital of nanjing medical univercity , China HAI XU
  • - Kantou Rousai Hospital , Japan KAORU SUMIDA
  • - Secomedic Hospital , Japan FUMINORI MIYOSHI
  • - Osaka Red Cross Hospital , Japan YANG WANG
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