대한흉부영상의학회 Korean Society of Thoracic Radiology

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Weekly Chest CasesArchive of Old Cases

Case No : 1396 Date 2024-07-22

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  • Courtesy of Seulgi You, Joo Sung Sun / Ajou University Hospital
  • Age/Sex 63 / F
  • Chief Complaint10days URI Sx, mild fever
  • Figure 1
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  • Figure 3
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  • Figure 5
  • Figure 6
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  • Figure 8

Diagnosis With Brief Discussion

Diagnosis
Granulomatosis with polyangiitis (GPA)
Radiologic Findings
Fig 1. Chest PA shows several nodular opacities in Lt lung.
Fig 2-8. CT scans reveals multiple nodular opacities and consolidations in both lungs. Lesions show enhancement. Some nodules showed well defined margin and consolidation showed irregular shape.
Brief Review
Granulomatosis with polyangiitis (GPA) was confirmed through surgical wedge resection. Five months after diagnosis, the patient complained of left eye swelling. An orbital MRI revealed an enhancing infiltrative lesion in the left orbital apex fat and diffuse mucoepithelial thickening with heterogeneous enhancement in bilateral paranasal sinuses. Surgical biopsy confirmed GPA involvement.


Granulomatosis with polyangiitis (GPA), formerly known as Wegener granulomatosis, is an antineutrophil cytoplasmic antibody (ANCA)
References
1. Guzman-Soto MI et al., Radiographics. 2021 Nov-Dec;41(7):1973-1991. doi: 10.1148/rg.2021210132.
2. Ananthakrishnan L et al., Am J Roentgenol. 2009 Mar;192(3):676-82. doi: 10.2214/AJR.08.1837.
Keywords

No. of Applicants : 59

▶ Correct Answer : 9/59,  15.3%
  • - Saitama-Sekishinkai Hosptal , Japan MIHOKO YAMAZAKI
  • - University of Yamanashi , Japan HIROYUKI MORISAKA
  • - The University of Tokyo Hospital , Japan TOSHIHIRO FURUTA
  • - , Japan YOSHIKI ISHII
  • - Nankai medical center , Japan NORITAKA KAMEI
  • - , Korea (South) HEONSEOK LEE
  • - Mie university , Japan SHIKO OKABE
  • - Korea University Anam Hospital , Korea (South) KYU-CHONG LEE
  • - , Sweden MOHAMAD TLASS
▶ Correct Answer as Differential Diagnosis : 10/59,  16.9%
  • - Kyoto University , Japan AKIHIKO SAKATA
  • - Other , Korea (South) SEONGSU KANG
  • - Oita University, Faculty of Medicine , Japan FUMITO OKADA
  • - Osaka University , Japan AKINORI HATA
  • - Other , Korea (South) HYEJOO PARK
  • - University of Yamanashi , Japan HIROAKI WATANABE
  • - Osaka metropolitan university Hospital , Japan TATSUSHI OURA
  • - Dokkyo Medical University , Japan HIROAKI ARAKAWA
  • - Hyogo Prefectural Kobe Children , Japan SHUHEI NORIMOTO
  • - Kantou Rousai Hospital , Japan KAORU SUMIDA
▶ Semi-Correct Answer : 5/59,  8.5%
  • - ZIGONG TCM HOSPITAL OF CHINA , China CAO CUN YOU
  • - MAGNUM DIAGNOSTICS - Goa INDIA , India PARESH K DESAI
  • - Avrasya Hospital/ISTANBUL , Turkey MURAT ULUSOY
  • - Kyoto University , Japan SHO KOYASU
  • - University of Yamanashi , Japan KOJIRO ONOHARA
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