Weekly Chest CasesArchive of Old Cases

Case No : 1420 Date 2025-01-06

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  • Courtesy of Sung Shine Shim, Woocheol Kwon / Ewha Womans University Seoul Hospital
  • Age/Sex 72 / M
  • Chief ComplaintDyspnea for 3 months
  • Figure 1
  • Figure 2
  • Figure 3
  • Figure 4
  • Figure 5
  • Figure 6
  • Figure 7

Diagnosis With Brief Discussion

Diagnosis
Extramedullary plasmacytoma in mediastinum
Radiologic Findings
Fig 1. A chest PA view shows mediastinal widening and bilateral pleural effusions.
Figs 2-5. CT scans reveal a large, enhancing soft tissue mass involving the middle and posterior mediastinum. The mass encases the superior vena cava, right main and lobar pulmonary arteries, and the left main bronchus.
Figs 6-7. Fused PET/CT images show a moderately hypermetabolic lesion (SUVmax 7.4) in the mediastinum.
Brief Review
This case illustrates a rare presentation of a plasmacytoma predominantly involving the mediastinal lymph nodes mimicking a mediastinal lymphoma. It is necessary to exclude plasmacytomas formed in extramedullary locations from bone marrow lesions, as observed in multiple myeloma. More than 80% of tumors occur in the upper respiratory tract, such as the nasopharynx, paranasal sinuses, nasal cavity, oropharynx, and tonsils. In non
References
1. Masood A, Hudhud KH, Hegazi A, Syed G. Mediastinal plasmacytoma with multiple myeloma presenting as a diagnostic dilemma. Cases J 2008;1:116.
2. Miyazaki T, Kohno S, Sakamoto A, Komori K, Sasagawa I, Futagawa S, et al. A rare case of extramedullary plasmacytoma in the mediastinum. Intern Med 1992;31:1363
Keywords

No. of Applicants : 65

▶ Correct Answer : 2/65,  3.1%
  • - University of Yamanashi , Japan TAKAAKI HASHIMOTO
  • - University of Yamanashi , Japan KOJIRO ONOHARA
▶ Correct Answer as Differential Diagnosis : 6/65,  9.2%
  • - Kyoto University , Japan AKIHIKO SAKATA
  • - McGill University Health Center , Canada ALEXANDRE SEMIONOV
  • - Oita university , Japan AYUMI KAMEI
  • - , Korea (South) DONG-HO BANG
  • - Shiga General Hospital , Japan YUSAKU MORIBATA
  • - the first affiliatited hospital of nanjing medical univercity , China HAI XU
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