Discussion
Diagnosis With Brief Discussion
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- Imaging Findings
- Diffuse GGO with ill-defined nodules
Hepatosplenomegaly
Minimal pleural and pericardial effusion
- Discussion
- Malignant endotheliomatosis, Angiotropic large cell lymphoma
Malignant lymphoma characterized by proliferation of neoplastic lymphoid cells within the vascular lumen
Predominantly affects vessels in CNS
Lung involvement at autopsy: ~60%
CXR
Diffuse interstitial infiltrates
Normal, minimal bilateral pleural effusion
HRCT
Patchy areas of GGO of peripheral predominance with mild septal thickening
RPC; expanded alveolar septa and perivascular spaces due to distended septal capillaries, venules, and arterioles, filled with neoplastic cells, alveolar congestion and hemorrhage
- Keywords
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Lung, Lymphproliferative disorder,