대한흉부영상의학회 Korean Society of Thoracic Radiology

Discussion

Diagnosis With Brief Discussion

Courtesy

K

Discussion

Bleomycin is used in the treatment of squamous cell carcinoma, lymphoma and testicular neoplasms.
It is concentrated in the lung, which is therefore a primary target for adverse effects.
Toxicity is related to the cumulative dose and significantly increased when doses exceed a total of 400mg.
The frequency and severity of pulmonary toxicity increase with age, prior or concomitant radiation therapy, oxygen therapy, decreased renal function, or concomitant treatment with other chemotherapeutic agents.

Keywords

Lung, Iatrogenic lung disease, Drug complication,