Discussion
Diagnosis With Brief Discussion
- Courtesy
- Samsung Medical Center
- Discussion
- - Ubiquitous zoonotic disease
- Systemic infection usually producing fever with hepatorenal involvement, meningoencephalitis, and hemorrhage
- Pulmonary involvement (59.1%) with hemoptysis (37.4%)
- Radiological evidence of bilateral reticulonodular infiltration (60-91%) after 3-7 days symptom onset; progresses into extensive confluent consolidation
- Brochoscopy explorations with bronchoalveolar lavage: intra-alveolar hemorrhage, probably due to extensive area of endothelial damage by the toxins produced by leptospira rather than coagulation abnormality
- Prognosis: usually resolves in 5-10 days, occasionally develops ARDS
- Treatment: high dose glucocorticoid should be given as early as possible after the onset of dyspnea to all the patients with pulmonary involvement
- Keywords
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Lung, Infection, Bacterial infection,